Description
CytoNorm is an algorithm developed by the Saeys Lab for the purposes of normalizing batch effects between different datatsets, for combined analysis. It works by running FlowSOM in the background and aligning control samples from each batch, then applying that aligned 'spline' to batches, and exporting a batch effect corrected set of data files. *Note: CytoNorm v1.2 and newer will only work with R version 4.1 and newer. Users using older versions of R should use CytoNorm v1.1.2 and read the special installation instructions in the CytoNorm plugin folder.
Algorithm Authors
Sofie Van Gassen
Plugin Developers
Citation
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Categories
Quality Control
Normalization and Calibration